Association of Drug Metabolic Enzyme Genetic Polymorphisms and Adverse Drug Reactions in Patients Receiving Rifapentine and Isoniazid Therapy for Latent Tuberculosis

Weekly rifapentine and isoniazid therapy (3HP) is the most frequent treatment for latent tuberculosis infection (LTBI). However, the association between major adverse drug reactions (ADRs) and drug metabolic enzyme single-nucleotide polymorphisms (SNPs) remains unclear. In this study, 377 participan...

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Detalhes bibliográficos
Publicado no:Int J Environ Res Public Health
Main Authors: Yu, Ya-Yen, Tsao, Shih-Ming, Yang, Wen-Ta, Huang, Wei-Chang, Lin, Ching-Hsiung, Chen, Wei-Wen, Yang, Shun-Fa, Chiou, Hui-Ling, Huang, Yi-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981901/
https://ncbi.nlm.nih.gov/pubmed/31892222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijerph17010210
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