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Getting Personal with Neoantigen-Based Therapeutic Cancer Vaccines

Despite years of preclinical efforts and hundreds of clinical studies, therapeutic cancer vaccines with the routine ability to limit or eliminate tumor growth in humans have been elusive. With advances in genome sequencing, it is now possible to identify a new class of tumor-specific antigens derive...

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Detalhes bibliográficos
Main Authors: Hacohen, Nir, Fritsch, Edward F., Carter, Todd A., Lander, Eric S., Wu, Catherine J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033902/
https://ncbi.nlm.nih.gov/pubmed/24777245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-13-0022
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