The late endosomal p14–MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration

Cell migration is mediated by the dynamic remodeling of focal adhesions (FAs). Recently, an important role of endosomal signaling in regulation of cell migration was recognized. Here, we show an essential function for late endosomes carrying the p14–MP1 (LAMTOR2/3) complex in FA dynamics. p14–MP1-po...

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Hlavní autoři: Schiefermeier, Natalia, Scheffler, Julia M., de Araujo, Mariana E.G., Stasyk, Taras, Yordanov, Teodor, Ebner, Hannes L., Offterdinger, Martin, Munck, Sebastian, Hess, Michael W., Wickström, Sara A., Lange, Anika, Wunderlich, Winfried, Fässler, Reinhard, Teis, David, Huber, Lukas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2014
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033770/
https://ncbi.nlm.nih.gov/pubmed/24841562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201310043
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