Development and validation of an LC-MS/MS assay for the quantification of the trans-methylation pathway intermediates S-adenosylmethionine and S-adenosylhomocysteine in human plasma

BACKGROUND: Although increased levels of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) have been implicated as markers for renal and vascular dysfunction, until now there have been no studies investigating their association with clinical post-transplant events such as organ rejection a...

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Main Authors: Klepacki, Jacek, Brunner, Nina, Schmitz, Volker, Klawitter, Jelena, Christians, Uwe, Klawitter, Jost
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033670/
https://ncbi.nlm.nih.gov/pubmed/23499573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cca.2013.03.003
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