Aberrant Muscle Antigen Exposure in Mice Is Sufficient to Cause Myositis in a Treg Cell–Deficient Milieu

OBJECTIVE: Myositis is associated with muscle-targeted inflammation and is observed in some Treg cell–deficient mouse models. Because an autoimmune pathogenesis has been strongly implicated, the aim of this study was to investigate the hypothesis that abnormal exposure to muscle antigens, as observe...

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Bibliographische Detailangaben
Hauptverfasser: Young, Nicholas A, Sharma, Rahul, Friedman, Alexandra K, Kaffenberger, Benjamin H, Bolon, Brad, Jarjour, Wael N
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2013
Schlagworte:
Myositis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033530/
https://ncbi.nlm.nih.gov/pubmed/24022275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38184
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