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A new molecular explanation for age-related neurodegeneration: The Tyr682 residue of amyloid precursor protein

Emerging evidence supports the role for the intracellular domains of amyloid precursor protein (APP) in the physiology and function of APP. In this short report, I discuss the hypothesis that mutation of Tyr682 on the Y(682)ENPTY(687) C-terminal motif of APP may be directly or indirectly associated...

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Detalhes bibliográficos
Autor principal: Matrone, Carmela
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033529/
https://ncbi.nlm.nih.gov/pubmed/23943322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300041
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