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Amyloid precursor protein: more than just neurodegeneration

Amyloid precursor protein (APP) fascinates cell biologists because it is proteolytically processed to generate multiple peptides, including amyloid-β, which is implicated in Alzheimer's disease. However, a large body of data also shows that the extracellular soluble fragment of APP produced by...

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Detalhes bibliográficos
Main Authors: Pimplikar, Sanjay W, Ghosal, Kaushik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308036/
https://ncbi.nlm.nih.gov/pubmed/22000643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt80
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