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Detection of promoter hypermethylation of Wnt antagonist genes in fecal samples for diagnosis of early colorectal cancer

AIM: To investigate the feasibility of detecting aberrantly hypermethylated Wnt-antagonist gene promoters (SFRP2 and WIF-1) in fecal DNA as non-invasive biomarkers for early colorectal cancer (CRC). METHODS: The methylation-specific polymerase chain reaction assay was performed to blindly analyze th...

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Sonraí Bibleagrafaíochta
Main Authors: Zhang, Hu, Zhu, You-Qing, Wu, Ya-Qiong, Zhang, Ping, Qi, Jian
Formáid: Artigo
Teanga:Inglês
Foilsithe: Baishideng Publishing Group Inc 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033472/
https://ncbi.nlm.nih.gov/pubmed/24876755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i20.6329
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