Melanoma Development and Progression Are Associated with Rad6 Upregulation and β-Catenin Relocation to the Cell Membrane

We have previously demonstrated that Rad6 and β-catenin enhance each other's expression through a positive feedback loop to promote breast cancer development/progression. While β-catenin has been implicated in melanoma pathogenesis, Rad6 function has not been investigated. Here, we examined the...

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Main Authors: Rosner, Karli, Mehregan, Darius R., Kirou, Evangelia, Abrams, Judith, Kim, Seongho, Campbell, Michelle, Frieder, Jillian, Lawrence, Kelsey, Haynes, Brittany, Shekhar, Malathy P. V.
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033428/
https://ncbi.nlm.nih.gov/pubmed/24891954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/439205
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