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Aberrant Chloride Intracellular Channel 4 Expression Contributes to Endothelial Dysfunction in Pulmonary Arterial Hypertension

BACKGROUND: Chloride intracellular channel 4 (CLIC4) is highly expressed in the endothelium of remodelled pulmonary vessels and plexiform lesions of patients with pulmonary arterial hypertension (PAH). CLIC4 regulates vasculogenesis through endothelial tube formation. Aberrant CLIC4 expression may c...

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Detaylı Bibliyografya
Asıl Yazarlar: Wojciak-Stothard, Beata, Abdul-Salam, Vahitha B., Lao, Ka Hou, Tsang, Hilda, Irwin, David C., Lisk, Christina, Loomis, Zoe, Stenmark, Kurt R., Edwards, John C, Yuspa, Stuart H., Howard, Luke S., Edwards, Robert J., Rhodes, Christopher J., Gibbs, J Simon R., Wharton, John, Zhao, Lan, Wilkins, Martin R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033409/
https://ncbi.nlm.nih.gov/pubmed/24503951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.006797
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