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Vasopressin-2 Receptor Signaling and Autosomal Dominant Polycystic Kidney Disease: From Bench to Bedside and Back Again

Blockade of the vasopressin-2 receptor (V2R) in the kidney has recently emerged as a promising therapeutic strategy in autosomal dominant polycystic kidney disease. The pathophysiologic basis of V2R-dependent cyst proliferation and disease progression, however, is not fully understood. Recent eviden...

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Bibliografiske detaljer
Main Authors: Rinschen, Markus M., Schermer, Bernhard, Benzing, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033383/
https://ncbi.nlm.nih.gov/pubmed/24556353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013101037
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