Stat3 Programs Th17-Specific Regulatory T Cells to Control GN

A pathogenic role for Th17 cells in inflammatory renal disease is well established. The mechanisms underlying their counter-regulation are, however, largely unknown. Recently, Th17 lineage-specific regulatory T cells (Treg17) that depend on activation of the transcription factor Stat3 were identifie...

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Autors principals: Kluger, Malte A., Luig, Michael, Wegscheid, Claudia, Goerke, Boeren, Paust, Hans-Joachim, Brix, Silke R., Yan, Isabell, Mittrücker, Hans-Willi, Hagl, Beate, Renner, Ellen D., Tiegs, Gisa, Wiech, Thorsten, Stahl, Rolf A.K., Panzer, Ulf, Steinmetz, Oliver M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2014
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033381/
https://ncbi.nlm.nih.gov/pubmed/24511136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013080904
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