Time Course of Pathogenic and Adaptation Mechanisms in Cystinotic Mouse Kidneys

Cystinosis, a main cause of Fanconi syndrome, is reproduced in congenic C57BL/6 cystinosin knockout (KO) mice. To identify the sequence of pathogenic and adaptation mechanisms of nephropathic cystinosis, we defined the onset of Fanconi syndrome in KO mice between 3 and 6 months of age and analyzed t...

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Bibliografiske detaljer
Main Authors: Gaide Chevronnay, Héloïse P., Janssens, Virginie, Van Der Smissen, Patrick, N’Kuli, Francisca, Nevo, Nathalie, Guiot, Yves, Levtchenko, Elena, Marbaix, Etienne, Pierreux, Christophe E., Cherqui, Stéphanie, Antignac, Corinne, Courtoy, Pierre J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2014
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033369/
https://ncbi.nlm.nih.gov/pubmed/24525030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013060598
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