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Dihydroartemisinin is a Hypoxia-Active Anti-Cancer Drug in Colorectal Carcinoma Cells

Tumor hypoxia is one main biological factor that drives resistance to chemotherapy and radiotherapy. To develop a novel strategy for overcoming hypoxia-induced therapy resistance, we examined the anti-neoplastic activity of the reactive oxygen donor dihydroartemisinin (DHA) in human colon cancer cel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ontikatze, Teona, Rudner, Justine, Handrick, René, Belka, Claus, Jendrossek, Verena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032948/
https://ncbi.nlm.nih.gov/pubmed/24904829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00116
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