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Using in vitro selection to direct the covalent attachment of human immunodeficiency virus type 1 Rev protein to high-affinity RNA ligands.

We have used an in vitro selection procedure called crosslinking SELEX (SELEX = systematic evolution of ligands by exponential enrichment) to identify RNA sequences that bind with high affinity and crosslink to the Rev protein from human immunodeficiency virus type 1 (HIV-1). A randomized RNA librar...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Jensen, K B, Atkinson, B L, Willis, M C, Koch, T H, Gold, L
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40328/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8618873/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.26.12220
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