Mitochondria hyperfusion and elevated autophagic activity are key mechanisms for cellular bioenergetic preservation in centenarians

Mitochondria have been considered for long time as important determinants of cell aging because of their role in the production of reactive oxygen species. In this study we investigated the impact of mitochondrial metabolism and biology as determinants of successful aging in primary cultures of fibr...

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Autors principals: Sgarbi, Gianluca, Matarrese, Paola, Pinti, Marcello, Lanzarini, Catia, Ascione, Barbara, Gibellini, Lara, Dika, Emi, Patrizi, Annalisa, Tommasino, Chiara, Capri, Miriam, Cossarizza, Andrea, Baracca, Alessandra, Lenaz, Giorgio, Solaini, Giancarlo, Franceschi, Claudio, Malorni, Walter, Salvioli, Stefano
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032796/
https://ncbi.nlm.nih.gov/pubmed/24799450
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