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Aging is associated with increased regulatory T-cell function
Regulatory T-cell (Treg, CD4(+)CD25(+)) dysfunction is suspected to play a key role in immune senescence and contributes to increased susceptibility to diseases with age by suppressing T-cell responses. FoxP3 is a master regulator of Treg function, and its expression is under control of several epig...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4032602/ https://ncbi.nlm.nih.gov/pubmed/24325345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12191 |
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