Compensatory Flux Changes within an Endocytic Trafficking Network Maintain Thermal Robustness of Notch Signaling

Developmental signaling is remarkably robust to environmental variation, including temperature. For example, in ectothermic animals such as Drosophila, Notch signaling is maintained within functional limits across a wide temperature range. We combine experimental and computational approaches to show...

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Hauptverfasser: Shimizu, Hideyuki, Woodcock, Simon A., Wilkin, Marian B., Trubenová, Barbora, Monk, Nicholas A.M., Baron, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032575/
https://ncbi.nlm.nih.gov/pubmed/24855951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.050
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