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Sphingosine kinase 1 cooperates with autophagy to maintain endocytic membrane trafficking

SphK1 associates with early endocytic membranes during endocytosis; however, the role of sphingosine or sphingosine-1-phosphate as the critical metabolite in endocytic trafficking has not been established. Here, we demonstrate that the recruitment of SphK1 to sphingosine-enriched endocytic vesicles...

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Publicado en:Cell Rep
Main Authors: Young, Megan M., Takahashi, Yoshinori, Fox, Todd E., Yun, Jong K., Kester, Mark, Wang, Hong-Gang
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123824/
https://ncbi.nlm.nih.gov/pubmed/27806293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.019
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