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Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis()

Autoantibodies to citrullinated protein antigens are specific markers of rheumatoid arthritis (RA). Although protein citrullination can be activated by numerous stimuli in cells, it remains unclear which of these produce the prominent citrullinated autoantigens targeted in RA. In these studies, we s...

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Bibliografski detalji
Glavni autori: Romero, Violeta, Fert-Bober, Justyna, Nigrovic, Peter A., Darrah, Erika, Haque, Uzma J., Lee, David M., van Eyk, Jennifer, Rosen, Antony, Andrade, Felipe
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032227/
https://ncbi.nlm.nih.gov/pubmed/24174326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006869
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