Impaired natural killer cell responses are associated with loss of the highly activated NKG2A(+)CD57(+)CD56(dim) subset in HIV-1 subtype D infection in Uganda

OBJECTIVE: Of the predominant HIV-1 subtypes in Uganda, subtype D infection confers a worse prognosis. HIV-1 infection causes perturbations to natural killer (NK) cells, and yet these cells can exert immune pressure on the virus and influence clinical outcome. Here, we studied NK cell activation and...

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Autores principales: Naluyima, Prossy, Eller, Michael A., Laeyendecker, Oliver, Quinn, Thomas C., Serwadda, David, Sewankambo, Nelson K., Gray, Ronald H., Michael, Nelson L., Wabwire-Mangen, Fred, Robb, Merlin L., Sandberg, Johan K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Basic Science: Concise Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032214/
https://ncbi.nlm.nih.gov/pubmed/24959961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000286
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