Innate and Adaptive Immune Responses Both Contribute to Pathological CD4 T Cell Activation in HIV-1 Infected Ugandans

HIV-1 disease progression is associated with persistent immune activation. However, the nature of this association is incompletely understood. Here, we investigated immune activation in the CD4 T cell compartment of chronically HIV-1 infected individuals from Rakai, Uganda. Levels of CD4 T cell acti...

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Main Authors: Eller, Michael A., Blom, Kim G., Gonzalez, Veronica D., Eller, Leigh Anne, Naluyima, Prossy, Laeyendecker, Oliver, Quinn, Thomas C., Kiwanuka, Noah, Serwadda, David, Sewankambo, Nelson K., Tasseneetrithep, Boonrat, Wawer, Maria J., Gray, Ronald H., Marovich, Mary A., Michael, Nelson L., de Souza, Mark S., Wabwire-Mangen, Fred, Robb, Merlin L., Currier, Jeffrey R., Sandberg, Johan K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079731/
https://ncbi.nlm.nih.gov/pubmed/21526194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018779
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