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All-trans retinoic acid induces Arg-1 and iNOS producing dendritic cells with T cell inhibitory function

Hepatic stellate cells (HSC) are a major source of the immunoregulatory metabolite all-trans retinoic acid (ATRA), which may contribute to the generation of tolerogenic dendritic cells (DCs) in the liver. The present study seeks to clarify the mechanism(s) through which ATRA promotes the development...

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Main Authors: Bhatt, Sumantha, Qin, Jie, Bennett, Carole, Qian, Shiguang, Fung, John J., Hamilton, Thomas A., Lu, Lina
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032093/
https://ncbi.nlm.nih.gov/pubmed/24790153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303073
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