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All-trans retinoic acid induces Arg-1 and iNOS producing dendritic cells with T cell inhibitory function

Hepatic stellate cells (HSC) are a major source of the immunoregulatory metabolite all-trans retinoic acid (ATRA), which may contribute to the generation of tolerogenic dendritic cells (DCs) in the liver. The present study seeks to clarify the mechanism(s) through which ATRA promotes the development...

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Detalhes bibliográficos
Main Authors: Bhatt, Sumantha, Qin, Jie, Bennett, Carole, Qian, Shiguang, Fung, John J., Hamilton, Thomas A., Lu, Lina
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032093/
https://ncbi.nlm.nih.gov/pubmed/24790153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303073
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