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Rare coding variation in paraoxonase-1 is associated with ischemic stroke in the NHLBI Exome Sequencing Project

HDL-associated paraoxonase-1 (PON1) is an enzyme whose activity is associated with cerebrovascular disease. Common PON1 genetic variants have not been consistently associated with cerebrovascular disease. Rare coding variation that likely alters PON1 enzyme function may be more strongly associated w...

সম্পূর্ণ বিবরণ

সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Kim, Daniel Seung, Crosslin, David R., Auer, Paul L., Suzuki, Stephanie M., Marsillach, Judit, Burt, Amber A., Gordon, Adam S., Meschia, James F., Nalls, Mike A., Worrall, Bradford B., Longstreth, W. T., Gottesman, Rebecca F., Furlong, Clement E., Peters, Ulrike, Rich, Stephen S., Nickerson, Deborah A., Jarvik, Gail P.
বিন্যাস: Artigo
ভাষা:Inglês
প্রকাশিত: The American Society for Biochemistry and Molecular Biology 2014
বিষয়গুলি:
অনলাইন ব্যবহার করুন:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031948/
https://ncbi.nlm.nih.gov/pubmed/24711634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P049247
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