Rare coding variation in paraoxonase-1 is associated with ischemic stroke in the NHLBI Exome Sequencing Project

HDL-associated paraoxonase-1 (PON1) is an enzyme whose activity is associated with cerebrovascular disease. Common PON1 genetic variants have not been consistently associated with cerebrovascular disease. Rare coding variation that likely alters PON1 enzyme function may be more strongly associated w...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Kim, Daniel Seung, Crosslin, David R., Auer, Paul L., Suzuki, Stephanie M., Marsillach, Judit, Burt, Amber A., Gordon, Adam S., Meschia, James F., Nalls, Mike A., Worrall, Bradford B., Longstreth, W. T., Gottesman, Rebecca F., Furlong, Clement E., Peters, Ulrike, Rich, Stephen S., Nickerson, Deborah A., Jarvik, Gail P.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2014
Teme:
Patient-Oriented and Epidemiological Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031948/
https://ncbi.nlm.nih.gov/pubmed/24711634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P049247
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki