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A COMPOSITE SCORING OF GENOTYPES DISCRIMINATES CORONARY HEART DISEASE RISK BEYOND CONVENTIONAL RISK FACTORS IN THE BOSTON PUERTO RICAN HEALTH STUDY
BACKGROUND AND AIMS: Using a genetic predisposition score (GPS), integrating the additive associations of a set of single nucleotide polymorphisms (SNPs) with CHD, we examined the consequences of the joint presence of a high GPS and conventional risk factors (CRFs). METHODS AND RESULTS: We studied e...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4031647/ https://ncbi.nlm.nih.gov/pubmed/19501493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.numecd.2009.03.016 |
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