Serotonin Reuptake Transporter Deficiency Modulates the Acute Thermoregulatory and Locomotor Activity Response to 3,4-(±)-Methylenedioxymethamphetamine, and Attenuates Depletions in Serotonin Levels in SERT-KO Rats

3,4-(±)-Methylenedioxymethamphetamine (MDMA) is a ring-substituted amphetamine derivative with potent psychostimulant properties. The neuropharmacological effects of MDMA are biphasic in nature, initially causing synaptic monoamine release, primarily of serotonin (5-HT), inducing thermogenesis and h...

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Autors principals: Lizarraga, Lucina E., Phan, Andy V., Cholanians, Aram B., Herndon, Joseph M., Lau, Serrine S., Monks, Terrence J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Neurotoxicology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031621/
https://ncbi.nlm.nih.gov/pubmed/24595820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu039
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