Chargement en cours...

Smoke Exposure Causes Endoplasmic Reticulum Stress and Lipid Accumulation in Retinal Pigment Epithelium through Oxidative Stress and Complement Activation

Age-related macular degeneration (AMD) is a complex disease caused by genetic and environmental factors, including genetic variants in complement components and smoking. Smoke exposure leads to oxidative stress, complement activation, endoplasmic reticulum (ER) stress, and lipid dysregulation, which...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kunchithapautham, Kannan, Atkinson, Carl, Rohrer, Bärbel
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031511/
https://ncbi.nlm.nih.gov/pubmed/24711457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.564674
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!