New Insights into the DT40 B Cell Receptor Cluster Using a Proteomic Proximity Labeling Assay

In the vertebrate immune system, each B-lymphocyte expresses a surface IgM-class B cell receptor (BCR). When cross-linked by antigen or anti-IgM antibody, the BCR accumulates with other proteins into distinct surface clusters that activate cell signaling, division, or apoptosis. However, the molecul...

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Détails bibliographiques
Auteurs principaux: Li, Xue-Wen, Rees, Johanna S., Xue, Peng, Zhang, Hong, Hamaia, Samir W., Sanderson, Bailey, Funk, Phillip E., Farndale, Richard W., Lilley, Kathryn S., Perrett, Sarah, Jackson, Antony P.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031500/
https://ncbi.nlm.nih.gov/pubmed/24706754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.529578
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