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An evolutionarily biased distribution of miRNA sites toward regulatory genes with high promoter-driven intrinsic transcriptional noise

BACKGROUND: miRNAs are a major class of regulators of gene expression in metazoans. By targeting cognate mRNAs, miRNAs are involved in regulating most, if not all, biological processes in different cell and tissue types. To better understand how this regulatory potential is allocated among different...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zare, Hossein, Khodursky, Arkady, Sartorelli, Vittorio
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031498/
https://ncbi.nlm.nih.gov/pubmed/24707827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-14-74
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