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Mechanical memory and dosing influence stem cell fate

We investigated whether stem cells remember past physical signals and whether these can be exploited to dose cells mechanically. We found that the activation of the Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding domain (TAZ) as well as the pre-osteogenic transcription...

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Hlavní autoři: Yang, Chun, Tibbitt, Mark W., Basta, Lena, Anseth, Kristi S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031270/
https://ncbi.nlm.nih.gov/pubmed/24633344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3889
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