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Mechanical memory and dosing influence stem cell fate

We investigated whether stem cells remember past physical signals and whether these can be exploited to dose cells mechanically. We found that the activation of the Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding domain (TAZ) as well as the pre-osteogenic transcription...

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Autori principali: Yang, Chun, Tibbitt, Mark W., Basta, Lena, Anseth, Kristi S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031270/
https://ncbi.nlm.nih.gov/pubmed/24633344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3889
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