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Mechanical memory and dosing influence stem cell fate

We investigated whether stem cells remember past physical signals and whether these can be exploited to dose cells mechanically. We found that the activation of the Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding domain (TAZ) as well as the pre-osteogenic transcription...

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Autors principals: Yang, Chun, Tibbitt, Mark W., Basta, Lena, Anseth, Kristi S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031270/
https://ncbi.nlm.nih.gov/pubmed/24633344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3889
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