Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition

Inhibitors of matrix metalloproteinases (MMPs) have been extensively explored to treat pathologies where excessive MMP activity contributes to adverse tissue remodeling. While MMP inhibition remains a relevant therapeutic target, MMP inhibitors have not translated to clinical application due to the...

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Detalhes bibliográficos
Main Authors: Purcell, Brendan P., Lobb, David, Charati, Manoj B., Dorsey, Shauna M., Wade, Ryan J., Zellers, Kia N., Doviak, Heather, Pettaway, Sara, Logdon, Christina B., Shuman, James, Freels, Parker D., Gorman, Joseph H., Gorman, Robert C., Spinale, Francis G., Burdick, Jason A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031269/
https://ncbi.nlm.nih.gov/pubmed/24681647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3922
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