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Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition

Inhibitors of matrix metalloproteinases (MMPs) have been extensively explored to treat pathologies where excessive MMP activity contributes to adverse tissue remodeling. While MMP inhibition remains a relevant therapeutic target, MMP inhibitors have not translated to clinical application due to the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Purcell, Brendan P., Lobb, David, Charati, Manoj B., Dorsey, Shauna M., Wade, Ryan J., Zellers, Kia N., Doviak, Heather, Pettaway, Sara, Logdon, Christina B., Shuman, James, Freels, Parker D., Gorman, Joseph H., Gorman, Robert C., Spinale, Francis G., Burdick, Jason A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031269/
https://ncbi.nlm.nih.gov/pubmed/24681647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3922
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