The Mucoid Switch in Pseudomonas aeruginosa Represses Quorum Sensing Systems and Leads to Complex Changes to Stationary Phase Virulence Factor Regulation

The opportunistic pathogen Pseudomonas aeruginosa chronically infects the airways of Cystic Fibrosis (CF) patients during which it adapts and undergoes clonal expansion within the lung. It commonly acquires inactivating mutations of the anti-sigma factor MucA leading to a mucoid phenotype, caused by...

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Main Authors: Ryall, Ben, Carrara, Marta, Zlosnik, James E. A., Behrends, Volker, Lee, Xiaoyun, Wong, Zhen, Lougheed, Kathryn E., Williams, Huw D.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031085/
https://ncbi.nlm.nih.gov/pubmed/24852379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096166
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