The Mucoid Switch in Pseudomonas aeruginosa Represses Quorum Sensing Systems and Leads to Complex Changes to Stationary Phase Virulence Factor Regulation

The opportunistic pathogen Pseudomonas aeruginosa chronically infects the airways of Cystic Fibrosis (CF) patients during which it adapts and undergoes clonal expansion within the lung. It commonly acquires inactivating mutations of the anti-sigma factor MucA leading to a mucoid phenotype, caused by...

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Autors principals: Ryall, Ben, Carrara, Marta, Zlosnik, James E. A., Behrends, Volker, Lee, Xiaoyun, Wong, Zhen, Lougheed, Kathryn E., Williams, Huw D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031085/
https://ncbi.nlm.nih.gov/pubmed/24852379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096166
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