Acetylcholinesterase Inhibitors with Photoswitchable Inhibition of β-Amyloid Aggregation

[Image: see text] Photochromic cholinesterase inhibitors were obtained from cis-1,2-α-dithienylethene-based compounds by incorporating one or two aminopolymethylene tacrine groups. All target compounds are potent acetyl- (AChE) and butyrylcholinesterase (BChE) inhibitors in the nanomolar concentrati...

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Main Authors: Chen, Xinyu, Wehle, Sarah, Kuzmanovic, Natascha, Merget, Benjamin, Holzgrabe, Ulrike, König, Burkhard, Sotriffer, Christoph A., Decker, Michael
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030803/
https://ncbi.nlm.nih.gov/pubmed/24628027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500016p
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