Loading...

A Ligand-Independent VEGFR2 Signaling Pathway Limits Angiogenic Responses in Diabetes

Although vascular complications are a hallmark of diabetes, the molecular mechanisms that underlie endothelial dysfunction are unclear. We showed that reactive oxygen species generated from hyperglycemia promoted ligand-independent phosphorylation of vascular endothelial growth factor receptor 2 (VE...

Full description

Saved in:
Bibliographic Details
Main Authors: Warren, Carmen M., Ziyad, Safiyyah, Briot, Anaïs, Der, Aaron, Iruela-Arispe, M. Luisa
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030697/
https://ncbi.nlm.nih.gov/pubmed/24399295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004235
Tags: Add Tag
No Tags, Be the first to tag this record!