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A Ligand-Independent VEGFR2 Signaling Pathway Limits Angiogenic Responses in Diabetes
Although vascular complications are a hallmark of diabetes, the molecular mechanisms that underlie endothelial dysfunction are unclear. We showed that reactive oxygen species generated from hyperglycemia promoted ligand-independent phosphorylation of vascular endothelial growth factor receptor 2 (VE...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4030697/ https://ncbi.nlm.nih.gov/pubmed/24399295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004235 |
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