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Cellular Extract Facilitates Nuclear Reprogramming by Altering DNA Methylation and Pluripotency Gene Expression

The functional reprogramming of a differentiated cell to a pluripotent state presents potential beneficial applications in disease mechanisms and regenerative medicine. Epigenetic modifications enable differentiated cells to perpetuate molecular memory to retain their identity. Therefore, the aim of...

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Detalhes bibliográficos
Main Authors: Xiong, Xian-Rong, Lan, Dao-Liang, Li, Jian, Zi, Xiang-Dong, Ma, Li, Wang, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030660/
https://ncbi.nlm.nih.gov/pubmed/24738992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2013.0078
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