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Increased immuno accessibility of MOMP epitopes in a vaccine formulated with amphipols may account for the very robust protection elicited against a vaginal challenge with C. muridarum

There is a need to implement a vaccine to protect against Chlamydia trachomatis infections. To test a new vaccine mice were immunized with the C. muridarum native major outer membrane protein (nMOMP) solubilized with either amphipol A8-35 or the detergent Z3-14. Ovalbumin was used as a negative cont...

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Bibliografische gegevens
Hoofdauteurs: Tifrea, Delia F., Pal, Sukumar, Popot, Jean-Luc, Cocco, Melanie J., de la Maza, Luis M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030638/
https://ncbi.nlm.nih.gov/pubmed/24778450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303392
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