Preferential Star Strand Biogenesis of Pre-miR-24-2 Targets PKC-alpha and Suppresses Cell Survival in MCF-7 Breast Cancer Cells

microRNAs (miRNA) are regulators of cellular pathways and alterations of normal miRNA expression levels have been shown to increase tumorigenesis. miR-24 has been demonstrated as having both tumor suppressive and oncogenic properties depending on cell context. Here we demonstrate a possible role for...

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Hauptverfasser: Martin, Elizabeth C., Elliott, Steven, Rhodes, Lyndsay V., Antoon, James W., Fewell, Claire, Zhu, Yun, Driver, Jennifer L., Jodari-Karimi, Mona, Taylor, Christopher W., Flemington, Erik K., Beckman, Barbara S., Collins-Burow, Bridgette M., Burow, Matthew E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030540/
https://ncbi.nlm.nih.gov/pubmed/22911661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21946
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