Insulin-Like Growth Factor-1 Signaling Regulates miRNA Expression in MCF-7 Breast Cancer Cell Line

In breast carcinomas, increased levels of insulin-like growth factor 1 (IGF-1) can act as a mitogen to augment tumorigenesis through the regulation of MAPK and AKT signaling pathways. Signaling through these two pathways allows IGF-1 to employ mechanisms that favor proliferation and cellular surviva...

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Detalhes bibliográficos
Main Authors: Martin, Elizabeth C., Bratton, Melyssa R., Zhu, Yun, Rhodes, Lyndsay V., Tilghman, Syreeta L., Collins-Burow, Bridgette M., Burow, Matthew E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511482/
https://ncbi.nlm.nih.gov/pubmed/23226206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049067
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