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Theranostic Gd(III)-lipid microbubbles for MRI-guided focused ultrasound surgery

We have synthesized a biomaterial consisting of Gd(III) ions chelated to lipid-coated, size-selected microbubbles for utility in both magnetic resonance and ultrasound imaging. The macrocyclic ligand DOTA-NHS was bound to PE headgroups on the lipid shell of pre-synthesized microbubbles. Gd(III) was...

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Bibliografiske detaljer
Main Authors: Feshitan, Jameel A., Vlachos, Fotis, Sirsi, Shashank R., Konofagou, Elisa E., Borden, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030396/
https://ncbi.nlm.nih.gov/pubmed/21993236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.09.026
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