Curcumin abrogates LPS-induced proinflammatory cytokines in RAW 264.7 macrophages. Evidence for novel mechanisms involving SOCS-1, -3 and p38 MAPK

Curcumin is the active compound in the extract of Curcuma longa rhizomes with anti-inflammatory properties mediated by inhibition of intracellular signalling. SOCS and MAPKinases are involved in the signalling events controlling the expression of IL-6, TNF-α and PGE(2), which have important roles on...

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Bibliographic Details
Main Authors: Guimarães, Morgana Rodrigues, Leite, Fábio Renato Manzoli, Spolidorio, Luís Carlos, Kirkwood, Keith Lough, Rossa, Carlos
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030384/
https://ncbi.nlm.nih.gov/pubmed/24011306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.archoralbio.2013.07.005
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