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FLAP pharmacological blockade modulates metabolism of endogenous tau in vivo 

FLAP (5-lipoxygenase-activating protein) is a protein widely distributed within the central nervous system whose function is to regulate the activation of the 5-Lipoxygenase enzyme. Although previous works show that pharmacological blockade of FLAP improve the amyloidotic phenotype of the Tg2576, it...

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Autors principals: Chu, J, Lauretti, E, Meco, A Di, Praticò, D
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030325/
https://ncbi.nlm.nih.gov/pubmed/24301651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2013.106
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