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Estrogen Signaling and the DNA Damage Response in Hormone Dependent Breast Cancers

Estrogen is necessary for the normal growth and development of breast tissue, but high levels of estrogen are a major risk factor for breast cancer. One mechanism by which estrogen could contribute to breast cancer is via the induction of DNA damage. This perspective discusses the mechanisms by whic...

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Bibliografiske detaljer
Hovedforfatter: Caldon, C. Elizabeth
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030134/
https://ncbi.nlm.nih.gov/pubmed/24860786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00106
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