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Recombinant tandem multi-linear neutralizing epitopes of human enterovirus 71 elicited protective immunity in mice

BACKGROUND: Human Enterovirus 71 (EV71) has emerged as the leading cause of viral encephalitis in children, especially in the Asia-Pacific regions. EV71 vaccine development is of high priority at present, and neutralization antibodies have been documented to play critical roles during in vitro and i...

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Bibliographic Details
Main Authors: Li, Yue-Xiang, Zhao, Hui, Cao, Rui-Yuan, Deng, Yong-Qiang, Han, Jian-Feng, Zhu, Shun-Ya, Ma, Jie, Liu, Long, Qin, E-De, Qin, Cheng-Feng
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030048/
https://ncbi.nlm.nih.gov/pubmed/24885030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-11-79
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