Intratumoral delivery of recombinant vaccinia virus encoding for ErbB2/Neu inhibits the growth of salivary gland carcinoma cells

BACKGROUND: The antitumor activity induced by intratumoral vaccination with poxvirus expressing a tumor antigen was shown to be superior to that induced by subcutaneous vaccination. Salivary gland carcinomas overexpress ErbB2. Trastuzumab, a monoclonal antibody to ErbB2, was proposed for salivary gl...

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Detalhes bibliográficos
Main Authors: Masuelli, Laura, Fantini, Massimo, Benvenuto, Monica, Sacchetti, Pamela, Giganti, Maria Gabriella, Tresoldi, Ilaria, Lido, Paolo, Lista, Florigio, Cavallo, Federica, Nanni, Patrizia, Schlom, Jeffrey, Modesti, Andrea, Bei, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029891/
https://ncbi.nlm.nih.gov/pubmed/24886178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-122
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