Local delivery of recombinant vaccinia virus encoding for neu counteracts growth of mammary tumors more efficiently than systemic delivery in neu transgenic mice

Recombinant vaccinia virus has been widely employed as a cancer vaccine in several clinical trials. In this study we explored, employing BALB/c mice transgenic for the rat neu oncogene, the ability of the recombinant vaccinia virus neu (rV-neuT) vaccine to inhibit growth of neu+ mammary carcinomas a...

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Autors principals: Masuelli, Laura, Marzocchella, Laura, Focaccetti, Chiara, Lista, Florigio, Nardi, Alessandra, Scardino, Antonio, Mattei, Maurizio, Turriziani, Mario, Modesti, Mauro, Forni, Guido, Schlom, Jeffrey, Modesti, Andrea, Bei, Roberto
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561760/
https://ncbi.nlm.nih.gov/pubmed/20364378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-010-0850-0
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